Maps & Directions | Louisiana, Missouri

Louisiana Visitors & Convention Bureau

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Louisiana, Missouri is located on the Mississippi River in Northeast Missouri approximately 75 miles north of St. Louis, Missouri, 224 miles east of Kansas City, Missouri and 320 miles south of Chicago, Illinois.

Access to Louisiana & Pike County: From St. Louis via interstate 70 West to U.S. highway 61 North / 55 miles, exit onto U.S. highway 54 east 10 miles to Louisiana.

--- From Kansas City via interstate 70 East through Columbia to U.S. highway 54 East, follow U.S. 54 to Louisiana.

--- From Chicago, IL via interstate 55 South to interstate 72 West exiting Pittsfield, IL exit & U.S. highway 54 West 25 miles crossing the Mississippi entering Louisiana.